Zestoretic (Lisinopril/Hydrochlorothiazide) Information

The active ingredients in Zestoretic are:

• Lisinopril: 10 mg or 20 mg per tablet
• Hydrochlorothiazide: 12.5 mg or 25 mg per tablet

Other inactive ingredients may include:

• Lactose
• Magnesium stearate
• Microcrystalline cellulose
• Polyvinyl alcohol

Common side effects include:

• Dizziness
• Headache
• Cough (from lisinopril)
• Fatigue
• Low blood pressure

Serious side effects requiring immediate medical attention:

• Severe allergic reactions (rash, swelling, difficulty breathing)
• Severe dizziness or fainting
• High potassium levels (muscle weakness, slow heart rate)
• Liver problems (yellowing of the skin or eyes, dark urine)

Zestoretic is taken orally, usually once a day, with or without food. Your doctor will determine the appropriate dosage based on your condition and medical history.

Important considerations:

• Take the medication at the same time each day for consistency.
• Monitor your blood pressure regularly to track your progress.
• Drink plenty of fluids and maintain a balanced diet while taking this medication.

Zestoretic can interact with certain medications. Inform your doctor about all other medications you are currently taking, including over-the-counter drugs, herbs, and supplements.

Common interactions include:

• Other blood pressure medications: May increase the risk of low blood pressure.
• Diuretics: May enhance the effects of Zestoretic, potentially leading to dehydration or low blood pressure.
• Potassium supplements: Taking potassium supplements with Zestoretic may cause dangerously high potassium levels.

Zestoretic usually begins to lower blood pressure within a few hours of taking the medication, but it may take up to 1-2 weeks to notice the full effects. Your doctor will monitor your blood pressure to adjust the dosage if necessary.

If you experience severe dizziness, fainting, swelling of the face or throat, or difficulty breathing, stop taking Zestoretic and seek emergency medical attention immediately.

For mild side effects like dizziness or headache, consult your doctor about adjusting your dosage or switching medications.